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Tamoxifen

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15 09, 2014

Bioequivalence of 20-mg once-daily Tamoxifen relative to 10-mg twice-daily Tamoxifen regimens for breast cancer

2017-04-26T12:34:59+00:00

Abstract PURPOSE: We studied the bioequivalence of a new once-daily regimen of tamoxifen citrate relative to the standard twice-daily regimen of tamoxifen citrate, an established antiestrogenic treatment for breast cancer. PATIENTS AND METHODS: Of 30 women with breast cancer, 27 completed this open, two-period, crossover randomized trial. During one 3-month period, patients took one standard [...]

15 08, 2014

Ten Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival

2017-04-26T12:34:59+00:00

For some women with Breast Cancer, taking adjuvant tamoxifen  for 10 years after primary treatment leads to a greater reduction in breast cancer recurrences and deaths than taking the drug for only 5 years, according to the results of a large international clinical trial. The findings from the ATLAS trial—presented at the San Antonio Breast Cancer Symposium  (SABCS) and published in The [...]